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Health: Italy Bread Gives You Kidney Cancer
Posted on Sunday, November 05 @ 14:38:45 EST by samantha |
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Food groups and renal cell carcinoma: A case-control study from Italy
THE LULU OF THE WEEK: BREAD GIVES YOU KIDNEY CANCER
Journal abstract below:
Food groups and renal cell carcinoma: A case-control study from Italy
By Francesca Bravi et al.
Although nutrition and diet have been related to renal cell carcinoma (RCC), the role of specific foods or nutrients on this cancer is still controversial. We evaluated the relation between a wide range of foods and the risk of RCC in an Italian case-control study including 767 patients (494 men and 273 women) younger than 79 years with incident, histologically confirmed RCC, and 1,534 controls (988 men and 546 women) admitted to the same hospitals as cases for a wide spectrum of acute, non-neoplastic conditions, not related to long term diet modifications. A validated and reproducible food frequency questionnaire, including 78 foods and beverages, plus a separate section on alcohol drinking, was used to assess patients' dietary habits 2 years before diagnosis or hospital admission. Multivariate odds ratios (OR) were obtained after allowance for energy intake and other major confounding factors. A significant direct trend in risk was found for bread (OR = 1.94 for the highest versus the lowest intake quintile), and a modest excess of risk was observed for pasta and rice (OR = 1.29), and milk and yoghurt (OR = 1.27). Poultry (OR = 0.74), processed meat (OR = 0.64) and vegetables (OR = 0.65) were inversely associated with RCC risk. No relation was found for coffee and tea, soups, eggs, red meat, fish, cheese, pulses, potatoes, fruits, desserts and sugars. The results of this study provide further indications on dietary correlates of RCC, and in particular indicate that a diet rich in refined cereals and poor in vegetables may have an unfavorable role on RCC.
(From International Journal of Cancer, 2006)
There appears to have been no control for socioeconimic status so at a quick guess I suspect that the authors have simply shown once again that the poor have poorer health. I don't know a lot about Italian dietary habits but I suspect that the poor eat more bread and the rich eat more meat. The journal must be very careless of its reputation to publish such rubbish.
Statistical note: The use of odds ratios and reliance on extreme quintiles can obscure that fact that the differences in the means were very small and may obscure not-uncommon curvilinear relationships. I would hazard a guess that if the relationship had been expressed as a biserial correlation between bread consumption and patient group the relationship would have been shown as very weak indeed. And weak relationships tend to be poorly replicable
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Article Rating
Average Score: 2
Votes: 2
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